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ea0032p186 | Cardiovascular Endocrinology & Lipid Metabolism | ECE2013

The effect of testosterone replacement on endothelial dysfunction, inflammation and insulin resistance in male hypogonadotrophic hypogonadism

Sonmez Alper , Taslipinar Abdullah , Aydogdu Aydogan , Tapan Serkan , Meric Coskun , Basaran Yalcin , Sertoglu Erdim , Yilmaz Mahmut I , Serdar Muhittin A , Ozgurtas Taner , Bolu Erol , Kutlu Mustafa

Objective: Metabolic disorders are common in patients with hypogonadism. Testosterone replacement therapy (TRT) significantly improves symptoms of testosterone deprivation such as mood, libido or musculoscelatal power. However, whether the metabolic and cardiovascular risk is improved is not clearly known. We aimed to search for the metabolic and cardiovascular effects of TRT.Design: Prospective study, performed in the outpatient units of Gulhane Medical...

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ePoster

ea0022p327 | Diabetes | ECE2010

Chitotriosidase activity predicts endothelial dysfunction in type 2 diabetes mellitus

Haymana Cem , Sonmez Alper , Tapan Serkan , Safer Umut , Celebi Gurkan , Ozturk Ozlem , Genc Halil , Dogru Teoman , Tasci Ilker , Erdem Gokhan , Taslipinar Abdullah , Aydogdu Aydogan , Yilmaz Mahmut I , Kurt Ismail , Kutlu Mustafa

The enzyme chitotriosidase (ChT) is secreted by activated macrophages and play active role in human immune response. ChT activity is increased in atherosclerosis in association to the extent of the disease. We investigated the relevance of ChT to endothelial functions and insulin resistance in patients with T2DM.Forty newly diagnosed and untreated patients with T2DM (male 17; age: 47.0±6.2 years) and 50 healthy volunteers (male 21; age: 50.2±8....

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Endocrine Abstracts

The effect of testosterone replacement on endothelial dysfunction, inflammation and insulin resistance in male hypogonadotrophic hypogonadism

Chitotriosidase activity predicts endothelial dysfunction in type 2 diabetes mellitus

BiosciAbstracts